Direct Oral Anticoagulants for Acute Venous Thromboembolism: Closing the Circle? Running title: Verhamme et al.; DOACs for acute venous thromboembolism
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منابع مشابه
Direct oral anticoagulants for acute venous thromboembolism: closing the circle?
I n the past decades, the two-stage treatment of initial paren-teral heparin followed by vitamin K antagonists has been the standard therapy for patients with acute venous thrombo-embolism (VTE). With the advent of direct oral anticoagu-lants (DOACs), previously known as new oral anticoagulants, this era has come to an end. In this issue of Circulation, Schulman et al 1 report on the results of...
متن کاملRecent advances in the treatment of venous thromboembolism in the era of the direct oral anticoagulants
The direct oral anticoagulants (DOACs) have now supplanted vitamin K antagonists (VKAs) for the treatment of venous thromboembolism (VTE). The DOACs include dabigatran, which inhibits thrombin, and rivaroxaban, apixaban, and edoxaban, which inhibit factor Xa. The DOACs are as effective for the prevention of recurrence as conventional VTE treatment, consisting of a parenteral anticoagulant follo...
متن کاملComparison of Dabigatran vs. Warfarin in Acute Vnous Thromboemboly: Systematic Review
abstract:Acute Venous Thromboembolism (VTE) is a common disease associated with the significant morbidity and mortality. We reviewed clinical outcomes systematically with Dabigatran as a direct oral anticoagulants (DOAC) for treatment of acute VTE. We used Ovide, PubMed, Cochrane (CENTRAL), EMBASE, Scopus, Science Direct, LILAC(for article written not English) and also Iranian database; Magiran...
متن کاملComparison of Dabigatran vs. Warfarin in Acute Vnous Thromboemboly: Systematic Review
abstract:Acute Venous Thromboembolism (VTE) is a common disease associated with the significant morbidity and mortality. We reviewed clinical outcomes systematically with Dabigatran as a direct oral anticoagulants (DOAC) for treatment of acute VTE. We used Ovide, PubMed, Cochrane (CENTRAL), EMBASE, Scopus, Science Direct, LILAC(for article written not English) and also Iranian database; Magiran...
متن کاملOptimizing the safety of treatment for venous thromboembolism in the era of direct oral anticoagulants.
Direct oral anticoagulants (DOACs) are rapidly replacing vitamin K antagonists (VKAs) for treatment of venous thromboembolism (VTE). The DOACs include dabigatran, which inhibits thrombin, and rivaroxaban, apixaban, and edoxaban, which inhibit factor Xa. When compared with conventional VTE treatment consisting of a parenteral anticoagulant followed by a VKA, the DOACs were equally effective for ...
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تاریخ انتشار 2013